All topics

94 publications

Gender-Affirming Surgery

Gender-affirming genital surgery research, including robotic peritoneal flap vaginoplasty, phalloplasty, metoidioplasty, complications, revisions, patient-reported outcomes, and registry work.

Representative Work

All Gender-Affirming Surgery Publications

Defining Uroplastics as a Collaborative Discipline at the Interface of Urology and Plastic Surgery

Sorenson TJ, Zhao L, Levine JP

Plastic and reconstructive surgery. Global open · 2026

The intersection between urology and plastic surgery represents an important collaborative frontier in modern reconstruction. Defects involving the genitourinary and perineal regions frequently require the coordinated expertise of both specialties to...

Outcomes Following Metoidioplasty and Phalloplasty Gender Affirming Surgery With Urethral Lengthening: A Modified Delphi Consensus Study

Blasdel G, Chen ML, Berli J, Dy G, Dugi D, Djordjevic M, Bizic M, Zhao L, Schechter L, Santucci R, Myers JB, Goodwin I, Nikolavsky D, Meltzer T, Watt A, Pariser J, Figler B, Kuzon W, Hadj-Moussa M, McCormick B, Brown LK, Nigriny JF, Moses RA

Urology · 2025

To generate surgeon consensus on metoidioplasty and phalloplasty gender-affirming surgery outcomes statements using a modified Delphi method. We invited metoidioplasty and phalloplasty gender-affirming surgery surgeons to anonymously participate in a...

Prostatic diseases in transgender women: A systematic review of diagnosis, risk, and management

Bourillon A, Guillot-Tantay C, Freton L, Zhao L, Mesnard B, Morel-Journel N, Mathieu R, Neuville P, Schirmann A, Peyronnet B, Madec FX

International journal of transgender health · 2025

Most transgender women have their prostate left in situ throughout and after their transition. Managing prostate‑related conditions in transgender women remains challenging due to the lack of clear recommendations. This review aims to summarize the...

Gender-affirming Vaginoplasty Using Robotic Peritoneal Flap Method: Long-term Outcomes of 500 Cases

Blasdel G, Hemal K, Dubach-Reinhold C, Parker A, Amro C, Zhao LC, Bluebond-Langner R

Annals of surgery · 2025

To determine the outcomes of robotic peritoneal flap vaginoplasty. There is a lack of long-term outcomes data for gender-affirming vaginoplasty to inform patient decision-making. A retrospective cohort of 500 consecutive patients undergoing robotic...

Quantifying the Learning Curve in Robotic Peritoneal Flap Vaginoplasty

Hemal K, Blasdel G, Parker A, Amro C, Dubach-Reinhold C, Zhao LC, Bluebond-Langner R

Annals of plastic surgery · 2025

The learning curve (LC) is the process of mastering a new technique. This study assesses the LC for robotic-assisted peritoneal flap gender-affirming vaginoplasty (RPGAV). A retrospective chart review of all consecutive patients undergoing RPGAV between...

Development and Assessment of a Patient-Reported Outcome Instrument for Gender-Affirming Care

Kaur MN, Rae C, Morrison SD, Laungani A, Brassard P, Mullender MG, van de Grift TC, Young-Afat DA, Sørensen JA, Poulsen L, Cornacchi SD, Graesser JG, Igbokwe MM, Satterwhite T, Pang JH, Akhavan AA, Hu A, Johnson N, Cano SJ, Savard K, Mundinger GS, Capitán-Cañadas F, Simon D, Capitán L, Coon D, Brydges HT, Bluebond-Langner R, Rodriguez ED, Zhao LC, Armstrong KA, Dean NR, Crittenden TA, Cannell ZA, Lane M, Haley CA, Hsu J, Dy GW, Peters BR, Berli JU, Milano CE, Lava CX, Fan KL, Del Corral GA, Kaoutzanis C, Kalia N, Higuchi T, Ganor O, Subedi S, Douglass LM, Hamidian Jahromi A, Hosseini HC, Ihnat J, Parikh N, Hu K, Alperovich M, Ray EC, Aref Y, Hassan BA, Liang F, Mundy L, Chen ML, Pusic AL, Klassen AF

JAMA network open · 2025

There is an urgent need for a validated gender-affirming care-specific patient-reported outcome measure (PROM). To field test the GENDER-Q, a new PROM for gender-affirming care, in a large, international sample of transgender and gender diverse (TGD)...

Bridging the evidence gap in gender-affirming care: urgent research needs

Dolendo I, Zhao L, Bluebond-Langner R, Anger JT

BJU international · 2025

Gender-affirming care has emerged as a critical component of healthcare, addressing the specific medical and psychosocial needs of transgender and non-binary individuals. In this review article, we address what we see as the most pressing evidence gaps in...

Exploring the Incidence of Testicular Neoplasms in the Transgender Population: A Case Series

Shanker EM, Ren Q, Zhao LC, Bluebond-Langner R, Deng FM

Archives of pathology & laboratory medicine · 2025

The use of hormonal therapy and gender-affirming surgery in the transgender community has been rising during the last several years. Although it is generally safe, hormonal therapy's link to testicular cancer remains uncertain. To review the incidence of...

Impact of Gender Affirming Vaginoplasty on Lower Urinary Tract Function: A Single-Center Prospective Cohort Study

Lee J, Oh C, Brucker B, Bluebond-Langner R, Zhao LC

Neurourology and urodynamics · 2024

With increased access to gender affirming care, the rate of vaginoplasties in the US has risen rapidly. Although some retrospective studies report high rates of lower urinary tract symptoms (LUTS) after gender affirming vaginoplasty, the type and severity...

Incidence, Complications, and Long-term Outcomes of Gender-affirming Phalloplasty: Analysis of a Large Statewide Population-based Dataset

Zhang TR, Harel D, Rivera A, Shahnawaz S, Qian Y, Berry C, Zhao LC, Radix A, Bluebond-Langner R, Mmonu NA

Urology · 2024

To evaluate the incidence of gender-affirming phalloplasty and postoperative complications in a large population-based dataset. Retrospective cohort study was done using the California Department of Health Care Access and Information datasets which include...

Pilot Test of A Gender-conscious Sexual Health Intake Questionnaire: Increasing Inclusivity and Mitigating Bias in Sexual History Taking

Zhang TR, Castle E, Dubach-Reinhold C, Blasdel G, Kloer C, Alford A, Bluebond-Langner R, Zhao LC

Plastic and reconstructive surgery. Global open · 2024

Sexual health is critical to overall health, yet sexual history taking is challenging. LGBTQ+ patients face additional barriers due to cis/heteronormativity from the medical system. We aimed to develop and pilot test a novel sexual history questionnaire...

Transgender and Non-Binary Surgery Registry: Building a Patient-Focused Registry for Genital Gender Affirming Surgery

Dy GW, Blasdel G, Dugi D, Butler C, Hotaling JM, Myers JB, Goodwin I, Bluebond-Langner R, Zhao LC, Agarwal CA

Transgender health · 2024

High quality data regarding long-term clinical and patient-reported outcomes (PROs) of genital gender-affirming surgery (GGAS) are lacking, and transgender and non-binary (TGNB) community voices have not historically been included in research development....

The Greatest Challenges after Gender-Affirming Vaginoplasty: A Qualitative Analysis

Blasdel G, Kloer C, Zarchen N, Bassale S, Zhao LC, Bluebond-Langner R, Dy GW

Transgender health · 2024

Gender-affirming vaginoplasty can involve profound postoperative challenges related to the typical healing process and potential complications. We present a qualitative analysis of the greatest challenges that individuals experience after vaginoplasty with...

Mending the Gap: AlloDerm as a Safe and Effective Option for Vaginal Canal Lining in Revision Robotic Assisted Gender Affirming Peritoneal Flap Vaginoplasty

Parker A, Brydges H, Blasdel G, Bluebond-Langner R, Zhao LC

Urology · 2023

To address instances when there is insufficient remnant tissue to perform revision following canal-deepening gender affirming vaginoplasty revisions as indicated by insufficient depth. Options for lining of the vaginal canal include skin grafts, peritoneal...

Does Genital Self-image Correspond with Sexual Health before and after Vaginoplasty?

Kloer C, Blasdel G, Shakir N, Parker A, Itzel Gómez A, Zhao LC, Bluebond-Langner R

Plastic and reconstructive surgery. Global open · 2023

Patient-reported outcomes regarding sexual health are lacking or have not been validated for transgender patients following vaginoplasty. The aim of this study is to further characterize the difference in sexual health, genital self-image, and the...

Anterolateral Thigh Phalloplasty With Staged Skin Graft Urethroplasty: Technique and Outcomes

Robinson I, Chao BW, Blasdel G, Levine JP, Bluebond-Langner R, Zhao LC

Urology · 2023

1) To describe the authors' technique of anterolateral thigh (ALT) phalloplasty with staged skin graft urethroplasty and 2) to report the surgical outcomes and complications of this technique in a preliminary patient cohort. Following IRB (Institutional...

Gender-Affirming Vaginoplasty: A Comparison of Algorithms, Surgical Techniques and Management Practices across 17 High-volume Centers in North America and Europe

Coon D, Morrison SD, Morris MP, Keller P, Bluebond-Langner R, Bowers M, Brassard P, Buncamper ME, Dugi D 3rd, Ferrando C, Gast KM, McGinn C, Meltzer T, Monstrey S, Özer M, Poh M, Satterwhite T, Ting J, Zhao L, Kuzon WM, Schechter L

Plastic and Reconstructive Surgery Global Open · 2023

Operative Management of Complications Following Intestinal Vaginoplasty: A Case Series and Systematic Review

Robinson IS, Cripps CN, Bluebond-Langner R, Zhao LC

Urology · 2023

To describe the authors' experience with surgical management of complications following intestinal vaginoplasty and review the literature on incidence of complications following gender-affirming intestinal vaginoplasty. Retrospective chart review...

Nipple-Preserving Inferior-Ellipse Mastectomy: A New Technique for Gender-Affirming Top Surgery

Robinson IS, Salibian A, Zhao LC, Bluebond-Langner R

Plastic and reconstructive surgery · 2023

The 2 most common techniques for gender-affirming mastectomy are the double-incision free nipple graft and periareolar techniques. However, some patients are not well suited for either technique. When the nipples are high and on the pectoralis muscle, but...

Urinary Reconstruction in Genital Gender-Affirming Surgery: Checking Our Surgical Complication Blind Spots

Blasdel G, Dy GW, Nikolavsky D, Ferrando CA, Bluebond-Langner R, Zhao LC

Plastic and reconstructive surgery · 2023

Urologic complications in genital gender-affirming surgery are imperfectly measured, with existing evidence limited by "blind spots" that will not be resolved through implementation of patient-reported outcomes alone. Some blind spots are expected in a...

Gender-Affirming Surgery in Adolescents and Young Adults: A Review of Ethical and Surgical Considerations

Robinson IS, Carswell JM, Boskey E, Agarwal CA, Brassard P, Bélanger M, Zhao LC, Bluebond-Langner R

Plastic and reconstructive surgery · 2023

The number of transgender adolescents seeking gender-affirming surgery (GAS) in increasing. Surgical care of the adolescent transgender patient is associated with several unique technical, legal, and ethical factors. The authors present a review of the...

How Should Surgeons Approach Gender-Affirming Surgery Revisions When Patients Were Not, Perhaps, Well Informed in Prior Counseling?

Zhao LC, Blasdel G, Parker A, Bluebond-Langner R

AMA journal of ethics · 2023

Surgeons often encounter patients with realistic goals yet who desire unrealistic means of achieving them. This tension is compounded when surgeons consult with patients eager to revise a prior gender-affirming procedure completed by another surgeon. Two...

Robotics in Gender Affirming Surgery: Current Applications and Future Directions

Robinson IS, Zhao LC, Bluebond-Langner R

Seminars in plastic surgery · 2023

Genital surgery for the treatment of gender dysphoria has undergone significant evolution since its inception in the first half of the 20th century. Robotic approaches to the pelvis allow for improved visualization and reduced abdominal wall morbidity,...

Perioperative Hormone Management in Gender-Affirming Mastectomy: Is Stopping Testosterone before Top Surgery Really Necessary?

Robinson IS, Rifkin WJ, Kloer C, Parker A, Blasdel G, Shakir N, Zhao LC, Bluebond-Langner R

Plastic and reconstructive surgery · 2022

Gender-affirming mastectomy, or "top surgery," has become one of the most frequently performed procedures for transgender and nonbinary patients. However, management of perioperative testosterone therapy remains controversial. Despite a lack of supporting...

Genital Hypoplasia before Gender-Affirming Vaginoplasty: Does the Robotic Peritoneal Flap Method Create Equivalent Vaginal Canal Outcomes?

Blasdel G, Kloer C, Parker A, Shakir N, Zhao LC, Bluebond-Langner R

Plastic and reconstructive surgery · 2022

Insufficient genital tissue has been reported as a barrier to achieving depth in gender-affirming vaginoplasty. The authors sought to characterize vaginal depth and revision outcomes in patients with genital hypoplasia undergoing robotic peritoneal flap...

External Genital Revisions after Gender-Affirming Penile Inversion Vaginoplasty: Surgical Assessment, Techniques, and Outcomes

Dy GW, Salibian AA, Blasdel G, Zhao LC, Bluebond-Langner R

Plastic and reconstructive surgery · 2022

Following gender-affirming penile inversion vaginoplasty or vulvoplasty, patients may seek vulvar revision procedures for a variety of common aesthetic and functional concerns. These indications for revision and accompanying techniques are not...

The Management of Intra-abdominal Complications Following Peritoneal Flap Vaginoplasty

Robinson IS, Blasdel G, Bluebond-Langner R, Zhao LC

Urology · 2022

To describe the authors' experience diagnosing and managing intra-abdominal complications following robotic peritoneal flap vaginoplasty. The peritoneal flap vaginoplasty is a technique used to achieve consistent vaginal depth regardless of available natal...

Familiar Infections in Novel Anatomy: Patient Reports of Sexually Transmitted Infections After Gender-Affirming Penile Reconstruction

Blasdel G, Robinson I, Parker A, Zhao LC, Bluebond-Langner R

Sexually transmitted diseases · 2022

Sexually transmitted infections (STIs) after penile reconstruction in transgender, nonbinary, and other gender expansive (T/GE) populations have not previously been described, despite known risk factors in the population. After T/GE penile reconstruction,...

Gender-affirming Phalloplasty: A Postoperative Protocol for Success

Rifkin WJ, Daar DA, Cripps CN, Mars G, Zhao LC, Levine JP, Bluebond-Langner R

Plastic and reconstructive surgery. Global open · 2022

Increased access to care and insurance coverage has led to an increase in gender-affirming surgeries performed in the United States. Gender-affirming phalloplasty has a variety of donor sites and surgical techniques including both pedicled and free flaps....

Gender-affirming Mastectomy: Comparison of Periareolar and Double Incision Patterns

Rifkin WJ, Robinson IS, Kloer C, Cripps CN, Boyd CJ, Blasdel G, Zhao LC, Bluebond-Langner R

Plastic and reconstructive surgery. Global open · 2022

Gender-affirming mastectomy has become one of the most frequently performed procedures for transgender and nonbinary patients. Although there are a variety of potential surgical approaches available, the impact of technique on outcomes remains unclear....

Recommendations for Communication in Gender-Affirming Surgical Care

Blasdel G, Parker AC, Salibian A, Robinson I, Zhao LC, Bluebond-Langner R

Plastic and reconstructive surgery · 2022

The surgical treatment of gender incongruence with gender-affirming surgery requires a sophisticated understanding of the substantial diversity in patient expectations and desired outcomes. There are patients with gender incongruence who desire surgical...

Coming Soon: Ability to Orgasm After Gender Affirming Vaginoplasty

Blasdel G, Kloer C, Parker A, Castle E, Bluebond-Langner R, Zhao LC

The journal of sexual medicine · 2022

Many patients have goals related to sexual health when seeking gender-affirming vaginoplasty, and previous investigations have only studied the ability to orgasm at cross-sectional timepoints. Our aim is to quantify the time to orgasm postoperative...

Incidence of Cancer and Premalignant Lesions in Surgical Specimens of Transgender Patients

Jacoby A, Rifkin W, Zhao LC, Bluebond-Langner R

Plastic and reconstructive surgery · 2021

Gender-affirming surgery is becoming increasingly more common. Procedures including chest masculinization, breast augmentation, vaginoplasty, metoidioplasty, and phalloplasty routinely generate discarded tissue. The incidence of finding an occult...

Robotic-assisted Vaginectomy During Staged Gender-affirming Penile Reconstruction Surgery: Technique and Outcomes

Jun MS, Shakir NA, Blasdel G, Cohen O, Levine JP, Bluebond-Langner R, Zhao LC

Urology · 2021

To report our novel technique and mid-term follow-up for robotic-assisted laparoscopic vaginectomy (RALV), a component procedure of staged gender-affirming penile reconstructive surgery. The records of patients seeking gender-affirming penile...

Surgical Outcomes Following Gender Affirming Penile Reconstruction: Patient-Reported Outcomes From a Multi-Center, International Survey of 129 Transmasculine Patients

Robinson IS, Blasdel G, Cohen O, Zhao LC, Bluebond-Langner R

The journal of sexual medicine · 2021

Current literature on surgical outcomes after gender affirming genital surgery is limited by small sample sizes from single-center studies. To use a community-based participatory research model to survey a large, heterogeneous cohort of transmasculine...

Robotic Peritoneal Flap Revision of Gender Affirming Vaginoplasty: a Novel Technique for Treating Neovaginal Stenosis

Dy GW, Blasdel G, Shakir NA, Bluebond-Langner R, Zhao LC

Urology · 2021

To present the technique and early outcomes of salvage neovaginal reconstruction using robotic dissection and peritoneal flap mobilization. Twenty-four patients underwent robotic peritoneal flap revision vaginoplasty from 2017 to 2020. A canal is dissected...

One or Two Stage Buccal Augmented Urethroplasty has a High Success Rate in Treating Post Phalloplasty Anastomotic Urethral Stricture

Beamer MR, Schardein J, Shakir N, Jun MS, Bluebond-Langner R, Zhao LC, Nikolavsky D

Urology · 2021

To describe the outcomes of single-stage and staged repairs in properly selected patients with phalloplasty anastomotic strictures. A bi-institutional retrospective review was performed of all patients who underwent anastomotic stricture repairs between...

Postulating Penis: What Influences the Interest of Transmasculine Patients in Gender Affirming Penile Reconstruction Techniques?

Parker A, Blasdel G, Kloer C, Kimberly L, Shakir N, Robinson I, Bluebond-Langner R, Zhao LC

The journal of sexual medicine · 2021

The limitations of metoidioplasty and phalloplasty have been reported as deterrents for transgender and other gender expansive individuals (T/GE) desiring gender affirming surgery, and thus penile transplantation, epithesis, and composite tissue...

Vaginal Canal Reconstruction in Penile Inversion Vaginoplasty with Flaps, Peritoneum, or Skin Grafts: Where Is the Evidence?

Salibian AA, Schechter LS, Kuzon WM, Bouman MB, van der Sluis WB, Zhao LC, Bluebond-Langner R

Plastic and reconstructive surgery · 2021

To optimize neovaginal dimensions, several modifications of the traditional penile inversion vaginoplasty are described. Options for neovaginal lining include skin grafts, scrotal flaps, urethral flaps, and peritoneum. Implications of these techniques on...

Robotic-assisted genitourinary reconstruction: current state and future directions

Shakir NA, Zhao LC

Therapeutic advances in urology · 2021

With the widespread dissemination of robotic surgical platforms, pathology previously deemed insurmountable or challenging has been treated with reliable and replicable outcomes. The advantages of precise articulation for dissection and suturing, tremor...

Outcomes of Gender Affirming Peritoneal Flap Vaginoplasty Using the Da Vinci Single Port Versus Xi Robotic Systems

Dy GW, Jun MS, Blasdel G, Bluebond-Langner R, Zhao LC

European urology · 2020

Robotic-assisted peritoneal flap gender-affirming vaginoplasty (RPGAV) with the da Vinci Xi system has been reported to be a safe alternative to traditional penile inversion vaginoplasty. Utilizing the Single Port (SP) robot system, our surgical approach...

Robotic Excision of Vaginal Remnant/Urethral Diverticulum for Relief of Urinary Symptoms Following Phalloplasty in Transgender Men

Cohen OD, Dy GW, Nolan IT, Maffucci F, Bluebond-Langner R, Zhao LC

Urology · 2019

To describe the technique of robotic remnant vaginectomy/excision of urethral diverticulum in transmen and report postoperative outcomes. Between 2015 and 2018, 4 patients underwent robotic remnant vaginectomy/excision of urethral diverticulum for relief...

Presenting Complications to a Reconstructive Urologist After Masculinizing Genital Reconstructive Surgery

Dy GW, Granieri MA, Fu BC, Vanni AJ, Voelzke B, Rourke KF, Elliott SP, Nikolavsky D, Zhao LC

Urology · 2019

To evaluate the presenting complications of patients to reconstructive urologists after masculinizing gender affirming genital reconstructive surgery (GRS) performed elsewhere. We identified patients who underwent revision surgery by one of the co-authors...

Robotic transanal minimally invasive rectal mucosa harvest

Howard KN, Zhao LC, Weinberg AC, Granieri M, Bernstein MA, Grucela AL

Surgical endoscopy · 2019

Buccal mucosal grafts (BMG) are traditionally used in urethral reconstruction. There may be insufficient BMG for applications requiring large grafts, such as urethral stricture after gender-affirming phalloplasty. Rectal mucosa in lieu of BMG avoids oral...

Multi-Institutional Outcomes of Minimally Invasive Harvest of Rectal Mucosa Graft for Anterior Urethral Reconstruction

Granieri MA, Zhao LC, Breyer BN, Voelzke BB, Baradaran N, Grucela AL, Marcello P, Vanni AJ

The Journal of urology · 2019

We report multi-institutional outcomes in patients who underwent urethroplasty with a rectal mucosa graft. We used the TURNS (Trauma and Urologic Reconstructive Network of Surgeons) database to identify patients who underwent urethral reconstruction with...

Robotic Davydov Peritoneal Flap Vaginoplasty for Augmentation of Vaginal Depth in Feminizing Vaginoplasty

Jacoby A, Maliha S, Granieri MA, Cohen O, Dy GW, Bluebond-Langner R, Zhao LC

The Journal of urology · 2019

Penile inversion vaginoplasty is the most common procedure for genital reconstruction in transwomen. While penile inversion vaginoplasty usually provides an excellent aesthetic result, the technique may be complicated by vaginal stenosis and inadequate...

Urologic Complications After Phalloplasty or Metoidioplasty

Nikolavsky D, Hughes M, Zhao LC

Clinics in plastic surgery · 2018

In the past decade, issues facing transgender individuals have come to the forefront of popular culture, political discourse, and medical study. The evaluating physician should have knowledge of the reconstructed anatomy, as well as potential postoperative...

Reconstructive Management Pearls for the Transgender Patient

Dy GW, Sun J, Granieri MA, Zhao LC

Current urology reports · 2018

A growing number of transgender patients are seeking gender-affirming genital reconstructive surgery (GRS). These complex procedures have high complication rates. We describe common surgical pitfalls in GRS and approaches for minimizing complications....

Urologic Sequelae Following Phalloplasty in Transgendered Patients

Nikolavsky D, Yamaguchi Y, Levine JP, Zhao LC

The Urologic clinics of North America · 2017

In recent years, the issues of the transgender population have become more visible in the media worldwide. Transgender patients at various stages of their transformation will present to urologic clinics requiring general or specialized urologic care....

Fasciocutaneous flap reinforcement of ventral onlay buccal mucosa grafts enables neophallus revision urethroplasty

Wilson SC, Stranix JT, Khurana K, Morrison SD, Levine JP, Zhao LC

Therapeutic advances in urology · 2016

Urethral strictures or fistulas are common complications after phalloplasty. Neourethral defects pose a difficult reconstructive challenge using standard techniques as there is generally insufficient ventral tissue to support a graft urethroplasty. We...